Keerthi Thirtamara Rajamani

This study shows that Shank3-deficient rats have altered neural activity in the mesoaccumbens pathway, leading to impaired social reward processing, and that manipulating VTA activity can normalize behavior.

This study shows human glioblastoma cells integrate into brain-wide neuronal circuits, exhibit diverse connectivity, and respond to neuromodulatory inputs like acetylcholine, which promotes invasion and survival.

This study develops a high-throughput in vivo Perturb-seq platform to analyze gene function across diverse cell types in the brain and peripheral nervous system, identifying cell type-specific transcriptional networks.

This study identifies the supramammillary nucleus as a target of PVH oxytocin neurons and shows its necessity for social recognition memory in rats.