Malaria-derived hemozoin alters chromatin remodelling and skews dendritic cell responses to subsequent bacterial infections
Gintare Lasaviciute, Kanwal Tariq, Anaswara Sugathan, Jaclyn E. Quin, Mareike Polenkowski, Ioana Bujila, Oleksii A. Skorokhod, Marita Troye‐Blomberg, Eva Sverremark‐Ekström, Ann‐Kristin Östlund Farrants
This study shows that malaria-derived hemozoin alters chromatin remodeling in dendritic cells, reducing their response to bacterial LPS and changing immune activation.
iScience · Jul 3, 2025Peer-reviewedCell Biology