Author

Monica E. Brown

Vanderbilt UniversityORCID 0000-0002-8697-2702Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Andreanna BurmaniD· 1 shared Cynthia Ramos· 1 shared Francisca Adeniran· 1 shared Izumi KajiiD· 1 shared James R. GoldenringiD· 1 shared Joseph T. RolandiD· 1 shared Michael MomohiD· 1 shared Sudiksha Rathan-KumariD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperPhysiology

Andreanna BurmanORCID

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1 paper

Recent·Most cited

Altered cellular metabolic pathway and epithelial cell maturation induced by MYO5B defects are partially reversible by LPAR5 activation

Michael Momoh, Sudiksha Rathan-Kumar, Andreanna Burman, Monica E. Brown, Francisca Adeniran, Cynthia Ramos, James R. Goldenring, Joseph T. Roland, Izumi Kaji

This study shows that MYO5B defects disrupt lipid metabolism and mitochondrial structure in intestinal epithelial cells, and that LPAR5 activation with Compound-1 can partially reverse these defects and improve intestinal function in MVID models.

American Journal of Physiology-Gastrointestinal and Liver Physiology · Oct 15, 2024Peer-reviewedPhysiology