NeuroscienceProceedings of the National Academy of SciencesPeer-reviewed
A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding
Lei Wang, Jun Young Park, Fengming Liu…·Young-Goo Han
This study shows CDK6 promotes oRG expansion and neocortical folding in mice, ferrets, and human cerebral organoids, with its function independent of kinase activity and disrupted by microcephaly-causing mutations.