Hongjian Jin

This study shows that targeting RBM39 with indisulam promotes natural killer cell activity and eradicates neuroblastoma regardless of cellular state plasticity.

This study shows that Hedgehog signaling regulates mitotic spindle orientation in neural progenitors and iPSCs by affecting astral microtubules and transcriptional regulation of microtubule dynamics.

This study creates two mouse models with conditional c-MYC activation in specific cell types, leading to distinct neuroendocrine tumors resembling human neuroblastoma and somatostatinoma.

This paper creates a spatial cell atlas of neuroblastoma, revealing tumor heterogeneity through multi-omics data and identifying spatial compartmentalization and signaling patterns.

This study shows CDK6 promotes oRG expansion and neocortical folding in mice, ferrets, and human cerebral organoids, with its function independent of kinase activity and disrupted by microcephaly-causing mutations.

CovidExpress provides an open-access database and tool for exploring SARS-CoV-2 related gene expression data across tissues and conditions, identifying common regulated genes and a potential FURIN feedback loop.

This study identifies MiDAC as a regulator of neurodevelopmental gene expression by modulating histone acetylation and neurite outgrowth.

XenoCP is a cloud-based tool that removes mouse reads from xenograft BAM files to improve RNA-seq and WGS analysis accuracy.