Author

Christopher Lee Wolfgang

Johns Hopkins UniversityORCID 0000-0002-8717-0373Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Laura DeLong WoodiD· 2 shared Andre LevchenkoiD· 1 shared Anirban MaitraiD· 1 shared Ankit ChhodaiD· 1 shared Anup Sharma· 1 shared Bethsebie Sailo· 1 shared Christine A. Iacobuzio–DonahueiD· 1 shared Denis WirtziD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

Laura DeLong WoodORCID

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2 papers

Recent·Most cited

Cancer BiologyCell ReportsPeer-reviewedAug 18, 2026

SPINK1-COL18A1 Crosstalk Shapes Epigenome and Drives Cancer Stemness in Pancreatic Ductal Adenocarcinoma

Haoyu Tang, Bethsebie Sailo, Xingbo Shang…·Nita Ahuja

This study identifies SPINK1 as a regulator of epigenomic states and stemness in PDAC through its interaction with COL18A1 and endostatin release.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsbioRxivPreprintOct 25, 2017

Computational discovery of tissue morphology biomarkers in very long-term survivors with pancreatic ductal adenocarcinoma

Jacob S. Sarnecki, Laura DeLong Wood, Christopher Lee Wolfgang…·Pei-Hsun Wu

The paper identifies tissue morphology biomarkers in long-term PDAC survivors using digital pathology and machine learning, finding reduced heterogeneity and extra-tumoral space features correlate with better survival.

DOI 10.1101/207969

𝕏 PostBluesky