Author

Dietmar Haltrich

BOKU UniversityORCID 0000-0002-8722-8176Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alexandra EssebieriD· 1 shared Ariane MoraiD· 1 shared Boštjan KobeiD· 1 shared Brad BaldersoniD· 1 shared Burkhard RostiD· 1 shared Connie M. RossiD· 1 shared Elizabeth M. J. GillamiD· 1 shared Gabriel FoleyiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Alexandra EssebierORCID

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1 paper

Recent·Most cited

Engineering indel and substitution variants of diverse and ancient enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP)

Gabriel Foley, Ariane Mora, Connie M. Ross, Scott Bottoms, Leander Sützl, Marnie L. Lamprecht, Julian Zaugg, Alexandra Essebier, Brad Balderson, Rhys Newell, Raine E. S. Thomson, Boštjan Kobe, Ross Thomas Barnard, Luke W. Guddat, Gerhard Schenk, , Mikael Bodén A

The paper introduces GRASP, a method for ancestral sequence reconstruction that handles large datasets and indels, demonstrating its ability to generate biologically active enzyme ancestors.

PLoS Computational Biology · Oct 24, 2022Peer-reviewedBioinformatics