Author

Yingfei Wang

The University of Texas Southwestern Medical CenterORCID 0000-0002-8723-252XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Ashwani KumariD· 1 shared Benjamin Prud’hommeiD· 1 shared Bettina MühlingiD· 1 shared Chao XingiD· 1 shared Chenliang WangiD· 1 shared David Bunk· 1 shared David HörliD· 1 shared Deepak Dharmadhikari· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Ashwani KumarORCID

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2 papers

Recent·Most cited

KDM6B sensitizes PARthanatos via suppression of O6-methylguanine DNA methyltransferase repair and sustained checkpoint response

Mingming Yang, Chenliang Wang, Mi Zhou, Lei Bao, Yanan Wang, Ashwani Kumar, Chao Xing, Weibo Luo, Yingfei Wang

This study identifies KDM6B as a key regulator of PARthanatos by modulating MGMT expression and checkpoint response in cancer cells exposed to alkylating agents.

bioRxiv · Dec 17, 2021 · PreprintMolecular Biology

Deciphering the regulatory logic of a Drosophila enhancer through systematic sequence mutagenesis and quantitative image analysis

Yann Le Poul, Yaqun Xin, Liucong Ling, Bettina Mühling, Rita Jaenichen, David Hörl, David Bunk, Hartmann Harz, Heinrich Leonhardt, Yingfei Wang, Elena Osipova, Mariam Museridze, Deepak Dharmadhikari, Eamonn Murphy, Remo Rohs, , Nicolas Gompel

The paper quantifies the spatial activity of a Drosophila enhancer through sequence mutagenesis and image analysis, revealing dense regulatory information and novel regulatory logic.

bioRxiv · Jun 24, 2020 · PreprintGenetics