Ylva Engström

This study identifies a non-transcriptional role for POU/Oct factors in maintaining spindle stability and chromosome segregation during mitosis in both Drosophila and human cells.

This study identifies mRNA stem-loops and their stability as key regulators of stop codon readthrough in Drosophila, refining computational predictions of this phenomenon.

The paper shows Bab2 activates JNK signaling in Drosophila wing discs, causing apoptosis in the posterior compartment and proliferation in the anterior, leading to developmental reprogramming.

The paper shows that stop codon readthrough of the Drosophila Drifter gene produces functional protein isoforms that regulate ecdysone levels and developmental transitions.

The paper investigates how variability in Hox transcription factor concentration is controlled during development, finding that an auto-regulatory switch reduces variability by changing the balance of activating and repressing isoforms.