NeurosciencebioRxivPreprint
Efficient in vivo pharmacological inhibition of deltaFOSB, an AP1 transcription factor, in brain
Sean McNeme, Anil Kumar, Yun Young Yim…·Gabby Rudenko
This paper demonstrates the creation of YL0441, a highly effective inhibitor of DeltaFOSB that reduces genomic DNA binding sites by ~94% in APP mice.
DOI 10.1101/2025.10.21.683721