Author

Thomas Delgado

University of Rochester MedicineORCID 0000-0002-8746-307XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:mouse· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Gail V.W. JohnsoniD· 3 shared Jacen EmersoniD· 2 shared Jeffrey W. KeilloriD· 2 shared Matthew Hong· 2 shared Anthony B. CrumiD· 1 shared Benjamin H. WeekleyiD· 1 shared Ian Pagan· 1 shared Ian S. MazeiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersNeuroscience

Gail V.W. JohnsonORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Transglutaminase 2 Deletion Enhances Astrocyte-to-Neuron Metabolic Support and Attenuates Subacute Pathology Following Repetitive Mild Traumatic Brain Injury

Thomas Delgado, Tanzil Mahmud Arefin, Ian Pagan, Benjamin H. Weekley, Joel Rodwell‐Bullock, Mohammad R. Chowdhury, Anthony B. Crum, Ian S. Maze, Paul S. Brookes, Julian P. Meeks, Gail V.W. Johnson

This study shows that deleting transglutaminase 2 improves metabolic support from astrocytes and reduces pathology after repetitive mild traumatic brain injury.

bioRxiv · Jul 21, 2026 · PreprintNeuroscience

Pharmacological inhibition of astrocytic transglutaminase 2 facilitates the expression of a neurosupportive astrocyte reactive phenotype in association with increased histone acetylation

Thomas Delgado, Jacen Emerson, Matthew Hong, Jeffrey W. Keillor, Gail V.W. Johnson

This study shows that inhibiting astrocytic TG2 with VA4 promotes a neurosupportive reactive phenotype through increased histone acetylation and altered transcriptional regulation.

bioRxiv · Apr 15, 2024 · PreprintNeuroscience

Pharmacological inhibition of astrocytic transglutaminase 2 facilitates the expression of a neurosupportive astrocyte reactive phenotype in association with increased histone acetylation

Thomas Delgado, Jacen Emerson, Matthew Hong, Jeffrey W. Keillor, Gail V.W. Johnson

This study shows that inhibiting astrocytic TG2 with VA4 promotes a neurosupportive reactive phenotype through increased histone acetylation and altered transcriptional regulation.

bioRxiv · Feb 6, 2023 · PreprintNeuroscience