Author

Fabien Gautier

Centre National de la Recherche ScientifiqueORCID 0000-0002-8764-8277Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Organism:mouse· 1

Frequent Co-Authors

Philippe Paul JuiniD· 2 shared Sophie Barillé‐NioniD· 2 shared Aurélie Fétiveau· 1 shared Catherine GuetteiD· 1 shared Elise Douillard· 1 shared Florian ChocteauiD· 1 shared Laurent MailletiD· 1 shared Lisenn Lalier-BretaudeauiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Philippe Paul JuinORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Allosteric regulation of BH3-in-groove interactions by tail anchors of BCL-xL complexes limits BH3 mimetic antagonism.

Laurent Maillet, Aurélie Fétiveau, Lisenn Lalier-Bretaudeau, Nena Martin, Sophie Barillé‐Nion, Catherine Guette, Fabien Gautier, Stéphane Télétchéa, Philippe Paul Juin

The paper shows that tail anchors of BCL-xL and PUMA modulate BH3-in-groove interactions, affecting BH3 mimetic antagonism and cell survival.

Nature Communications · Nov 22, 2025Peer-reviewedCell Biology

Antimitotic chemotherapy promotes tumor NF-kB secretory phenotype and immunosuppressive CXCR2+ neutrophils chemotaxis in triple-negative breast cancers

Florian Chocteau, Fabien Gautier, Vanessa Josso, Elise Douillard, Philippe Paul Juin, Sophie Barillé‐Nion

The paper shows antimitotic chemotherapy induces a NF-kB secretory phenotype in triple-negative breast cancer, promoting immunosuppressive CXCR2+ neutrophil chemotaxis, and demonstrates that CXCR2 inhibition enhances antitumor immunity.

bioRxiv · Dec 21, 2024 · PreprintCancer Biology