Author

Lloyd D. Harvey

University of PittsburghORCID 0000-0001-5934-9934Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 2 Organism:human· 2 Assay:metabolomics· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Ankit A. DesaiiD· 2 shared Michael W. PauciuloiD· 2 shared Mohit JainiD· 2 shared Mona AlotaibiiD· 2 shared Stephen Y. ChaniD· 2 shared Susan C. ChengiD· 2 shared Thomas BerteroiD· 2 shared William C. NicholsiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersSystems Biology

Ankit A. DesaiORCID

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2 papers

Recent·Most cited

Pulmonary primary oxysterol and bile acid synthesis as a predictor of outcomesin pulmonary arterial hypertension

Mona Alotaibi, Lloyd D. Harvey, William C. Nichols, Michael W. Pauciulo, Anna Ryan Hemnes, Tao Long, Jeramie D. Watrous, Arjana Begzati, Jaakko O. Tuomilehto, Aki Samuli Havulinna, Teemu Niiranen, Pekka Jousilahti, Veikko V Salomaa, Thomas Bertero, Nick H. Kim, , Mohit Jain

The paper identifies pulmonary primary oxysterol and bile acid synthesis as a prognostic biomarker for pulmonary arterial hypertension, outperforming current clinical risk scores.

American Journal of Respiratory and Critical Care Medicine · Jul 16, 2026Peer-reviewedSystems Biology

Genetic regulation and targeted reversal of lysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension

Lloyd D. Harvey, Mona Alotaibi, Yi‐Yin Tai, Ying Tang, Hee‐Jung J. Kim, Neil J. Kelly, Wei Sun, Chen-Shan Chen Woodcock, Sanya Arshad, Miranda K. Culley, Wadih El Khoury, Rong Xie, Yassmin Al Aaraj, Jingsi Zhao, Neha Hafeez, , Stephen Y. Chan

The paper identifies NCOA7's role in lysosomal function and inflammatory sterol metabolism in PAH, showing its deficiency exacerbates disease through oxysterol/bile acid generation.

Science · Jan 23, 2025Peer-reviewedPhysiology