NeuroscienceNature GeneticsPeer-reviewed
Spatial and single-nucleus transcriptomic analysis of genetic and sporadic forms of Alzheimer's Disease
Emily Miyoshi, Samuel Morabito, Caden M. Henningfield…·Vivek Swarup
This study uses spatial transcriptomics and single-nucleus RNA-seq to compare genetic and sporadic Alzheimer's Disease, finding similar spatial and cell-type specific changes between sporadic AD and AD in Down Syndrome.