Jeffery R. Wickens

Cholinergic interneurons of the dorsomedial striatum mediate winner-loser effects on social hierarchy dynamics in male mice.

This study investigates how cholinergic interneurons in the dorsomedial striatum influence social hierarchy dynamics in male mice by examining winner-loser effects on social ranking.

Acute drug induced parkinsonian akinesia is associated with reduced rate and increased regularity of neuronal activity in the pedunculopontine tegmental nucleus of unanesthetized rats

The paper examines the effects of acute drug-induced parkinsonism on neuronal firing rates and regularity in rats, finding reduced firing rates and increased regularity in the pedunculopontine tegmental nucleus.

Mechanism of dopamine traveling waves in the striatum: theory and experiment

The paper investigates the mechanism of dopamine traveling waves in the striatum using theoretical and experimental approaches, finding that cholinergic interneurons and dopamine axons interact to drive these waves.

Ventral motor thalamic input to prelimbic cortex mediates cost-benefit decision-making in rats

Coincidence of cholinergic pauses, dopaminergic activation and depolarization drives synaptic plasticity in the striatum

The paper shows that LTP at corticostriatal synapses requires the temporal coincidence of cholinergic pauses and dopaminergic activation, along with SPN depolarization.

Anterior corpus callosum modulates symmetric forelimb movements during spontaneous food handling behavior of rats.

This study shows that blocking the anterior corpus callosum in rats reduces symmetric bimanual movements during food handling and increases asymmetric movements, suggesting its role in coordinating bimanual actions.