Simon D. Fisher

The paper evaluates factors affecting brain-age prediction models using structural neuroimaging data from 35,683 individuals, finding optimal model performance with no site harmonization, age-binning, and a sample size of over 1,600.

This study shows that optogenetic activation of hypothalamic CRH neurons increases stress-related behaviors and reduces sucrose motivation, suggesting a role for these neurons in motivational drive.

This study identifies the role of amygdala-cortical interactions in striatal plasticity during goal-directed learning, showing that BLA input to PL is necessary for corticostriatal potentiation.

This study investigates how ventral striatopallidal neurons modulate orexin/hypocretin neuron activity in response to food and metabolic states, revealing their role in reward-seeking behavior.

The paper shows that LTP at corticostriatal synapses requires the temporal coincidence of cholinergic pauses and dopaminergic activation, along with SPN depolarization.