Nicolas X. Tritsch

This study investigates how dopamine signaling in the striatum influences corticostriatal circuits during behavior, finding that learning-related plasticity, not acute dopamine effects, shapes circuit function.

This study identifies two distinct modes of striatal dopamine release that independently control locomotion and learning.

This study shows that adolescent amphetamine exposure causes sex-specific changes in mesolimbic dopamine axons and PFC dopamine transporter expression in adulthood, with males showing increased vulnerability to drug effects.

The paper shows that ventral striatal dopamine increases after hippocampal sharp-wave ripples in mice, suggesting a link between hippocampal replay and dopamine signaling during memory processing.

The paper identifies ultraslow serotonin oscillations in the hippocampus that distinguish substates within NREM and waking, linking them to memory consolidation and arousal.

The paper shows that blue light can falsely trigger dopamine release measurements using RdLight1, questioning previous findings on cholinergic interneurons' role in dopamine release.

The paper investigates the mechanism of dopamine traveling waves in the striatum using theoretical and experimental approaches, finding that cholinergic interneurons and dopamine axons interact to drive these waves.

The paper investigates how cell-type-specific disruptions in cortico-striatal circuits in FXS model mice lead to repetitive behaviors and identifies potential therapeutic targets.

This study investigates the role of dopamine in motor vigor, showing that it acts permissively rather than directly specifying movement speed and amplitude.

The paper shows that dopamine and acetylcholine levels in the striatum of mice fluctuate spontaneously with the same temporal relationship as during reward, driven by glutamatergic afferents rather than direct interactions between the neuromodulators.

The paper shows that midbrain dopamine neurons use presynaptic GABA uptake and vesicular transport to achieve inhibitory co-transmission, bypassing the need for de novo GABA synthesis.

The paper shows dopamine modulates the size of projection neuron ensembles in the striatum, with effects altered in Parkinson's disease.