Joshua A. Goldberg

Synchronous activation of striatal cholinergic interneurons induces local serotonin release

The paper shows that synchronous activation of striatal cholinergic interneurons induces local serotonin release through a mechanism similar to dopamine release.

Phase delays between mouse globus pallidus neurons entrained by common oscillatory drive arise from their intrinsic properties, not their coupling

The paper investigates phase delays in correlated oscillations of mouse GPe neurons under common oscillatory input, showing these delays arise from intrinsic properties rather than network connectivity.

Mechanism of dopamine traveling waves in the striatum: theory and experiment

The paper investigates the mechanism of dopamine traveling waves in the striatum using theoretical and experimental approaches, finding that cholinergic interneurons and dopamine axons interact to drive these waves.

Non-uniform distribution of dendritic nonlinearities differentially engages thalamostriatal and corticostriatal inputs onto cholinergic interneurons

The paper investigates how non-uniform distribution of dendritic currents in cholinergic interneurons differentially processes thalamostriatal and corticostriatal inputs.

A tonic nicotinic brake controls spike timing in striatal spiny projection neurons

This study shows that tonic activation of 4β2 nicotinic acetylcholine receptors on GABAergic interneurons primes feedforward inhibition, shaping striatal output timing and synaptic plasticity.

Striatal neurons are recruited dynamically into collective representations of self-initiated and learned actions in freely-moving mice

The paper investigates how striatal neurons represent self-initiated and learned actions in freely-moving mice, finding dynamic recruitment of neurons into cell assemblies during learned behaviors.

α-Synuclein-induced Kv4 channelopathy in mouse vagal motoneurons causes non-motor parkinsonian symptoms

This study identifies a Kv4 channelopathy in mouse vagal motoneurons caused by α-synuclein overexpression, leading to impaired gastrointestinal motility as a non-motor prodromal symptom of Parkinson's disease.

Population dynamics and entrainment of basal ganglia pacemakers are shaped by their dendritic arbors

This study shows how dendritic arbor structure influences the phase response curves of SNr pacemakers, affecting their collective dynamics and entrainment.

Wave-like activity patterns in the neuropil of striatal cholinergic interneurons in freely moving mice represent their collective spiking dynamics

The paper uses endoscopic imaging to study cholinergic interneurons in freely moving mice, revealing traveling-wave-like activity patterns in the neuropil that reflect collective spiking dynamics.