Jeremy T.-H. Chang

Signaling induced biophysical disruption of repressed chromatin domains drives immune cell fate

The paper identifies H3 serine 28 phosphorylation as a mechanism driving chromatin derepression and immune cell fate transitions by disrupting repressive chromatin domains.

The Cousa objective: a long working distance air objective for multiphoton imaging in vivo

The paper introduces a long working distance air objective for multiphoton imaging in vivo, demonstrating its performance across multiple species and imaging systems.

Development of visual response selectivity in cortical GABAergic interneurons

This study shows that visual experience shapes orientation tuning in cortical GABAergic interneurons but not the reduction of widespread network activity.

Experience-dependent reorganization drives development of a binocularly unified cortical representation of orientation

This study shows that experience-dependent reorganization aligns three distinct neural representations into a unified binocular orientation map in ferret visual cortex.

Potassium channels contribute to activity-dependent scaling of dendritic inhibition

The paper shows voltage-gated potassium channels suppress GABAergic inhibition in dendrites but are inactivated by activity, enhancing inhibition and limiting calcium influx.