David Fitzpatrick

The paper shows retinal waves shape modular cortical activity patterns that predict future orientation preferences in visual cortex.

The paper introduces a long working distance air objective for multiphoton imaging in vivo, demonstrating its performance across multiple species and imaging systems.

This study identifies chandelier cells' role in adaptive motor control through axo-axonic inhibition and synaptic plasticity during learning.

The paper shows that feedforward-recurrent circuit alignment in the visual cortex develops after experience, leading to coherent sensory representations.

The paper shows that experience-driven reorganization of endogenous networks leads to the emergence of reliable cortical representations.

This study shows that visual experience shapes orientation tuning in cortical GABAergic interneurons but not the reduction of widespread network activity.

The paper shows that training improves visual discrimination in tree shrews by enhancing specific V1 neurons' responses to rewarded stimuli, which correlates with performance and persists beyond training.

The paper investigates how binocular synaptic networks in visual cortical neurons contribute to interocular response alignment through functional and structural analysis.

The paper challenges the Hebbian plasticity model by showing that cortical neuron selectivity arises from the total number of synapses, not strong individual inputs.

This paper shows that cortical area V2 in tree shrews uses a sinusoidal transform to represent retinal coordinates, deviating from the conventional orthogonal mapping seen in V1.

This study shows that experience-dependent reorganization aligns three distinct neural representations into a unified binocular orientation map in ferret visual cortex.

The paper introduces variants of the glutamate sensor iGluSnFR with improved brightness, broader concentration detection, and different emission colors for enhanced in vivo imaging.

The paper shows that local cortical connections generate large-scale modular correlations and fractures in spontaneous activity, predicting mature orientation column structure.

This paper introduces a method to achieve video-rate volumetric imaging of brain activity at synaptic resolution using Bessel foci in two-photon microscopy.