Author

Ryan E. Glass

Quest Diagnostics (United States)ORCID 0000-0002-8802-7288Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander J. ClarkeiD· 1 shared Audrey GérardiD· 1 shared Benjamin A. FisheriD· 1 shared Benjamin DemarcoiD· 1 shared Esther L. Jones EvansiD· 1 shared G MeadiD· 1 shared Gemma HarrisiD· 1 shared Han CaiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alexander J. ClarkeORCID

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1 paper

Recent·Most cited

Autoantigen TRIM21 (Ro52) assembles pro-inflammatory immune complexes following lytic cell death

Esther L. Jones Evans, Benjamin Demarco, Han Cai, Madelon M.E. de Jong, Sarah Hill, Marcus A. Widdess, Joannah R. Fergusson, Ryan E. Glass, Gemma Harris, G Mead, Yavuz F. Yazicioglu, Saba Nayar, Benjamin A. Fisher, Mark Steven Cragg, Alexander J. Clarke, , Lynn B. Dustin

The paper shows TRIM21 becomes an autoantigen by forming pro-inflammatory immune complexes after lytic cell death, which are taken up by macrophages and drive inflammation.

Science Immunology · Apr 17, 2026Peer-reviewedImmunology