Author

Han Cai

University of OxfordORCID 0009-0007-2242-6984Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:flow cytometry· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Audrey GérardiD· 2 shared Alexander J. ClarkeiD· 1 shared Ana Laura ChiodettiiD· 1 shared Andrew MuiriD· 1 shared Arianne C. RichardiD· 1 shared Benjamin A. FisheriD· 1 shared Benjamin DemarcoiD· 1 shared Esther L. Jones EvansiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Audrey GérardORCID

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2 papers

Recent·Most cited

ImmunologyScience ImmunologyPeer-reviewedApr 17, 2026

Autoantigen TRIM21 (Ro52) assembles pro-inflammatory immune complexes following lytic cell death

Esther L. Jones Evans, Benjamin Demarco, Han Cai…·Lynn B. Dustin

The paper shows TRIM21 becomes an autoantigen by forming pro-inflammatory immune complexes after lytic cell death, which are taken up by macrophages and drive inflammation.

4 citationstop 1%

humanproteomics

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ImmunologybioRxivPreprintMar 20, 2026

Transient immune landscape remodelling shapes CD8 T-cell priming during infection

Ana Laura Chiodetti, Han Cai, Andrew Muir…·Audrey Gérard

The paper shows that transient immune architecture changes during infection protect low-affinity CD8 T-cell priming from Treg inhibition, ensuring broad T-cell responses.

DOI 10.64898/2026.03.18.712682

mouseflow cytometry

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