Extensive mutual influences of SMC complexes shape 3D genome folding
Han Zhao, Lirong Shu, Shiyi Qin, Fangxuan Lyu, Fuhai Liu, En Lin, Sijian Xia, Baiyue Wang, Manzhu Wang, Fengnian Shan, Yinzhi Lin, Lin Zhang, Yufei Gu, Gerd A. Blobel, Kai Huang, Haoyue Zhang
This study investigates how SMC complexes interact during mitosis to shape 3D genome structure by engineering cohesin/condensin configurations on mitotic chromosomes.
Nature · Feb 26, 2025Peer-reviewedCell Biology