Author

Yinzhi Lin

Shenzhen Bay LaboratoryORCID 0000-0002-8968-4327Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:ChIP-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Baiyue Wang· 3 shared Fengnian ShaniD· 3 shared Fuhai LiuiD· 3 shared Lirong ShuiD· 3 shared Manzhu Wang· 3 shared Dannan Jing· 2 shared En Lin· 2 shared Gerd A. BlobeliD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMolecular Biology

Baiyue Wang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedJun 30, 2026

Distinct and compensatory roles of Stag1 and Stag2 in post-mitotic genome refolding

Manzhu Wang, Yabing Zhang, Fengnian Shan…·Haoyue Zhang

This study investigates the distinct and compensatory roles of Stag1 and Stag2 in post-mitotic genome refolding, showing Stag2's critical role in chromatin remodeling and transcription activation.

1 citation

humanChIP-seq

Cancer BiologyCell Death and DiseasePeer-reviewedFeb 28, 2026

Targeting fatty acid synthase suppresses tumor development in NF2/CDKN2A-deficient malignant pleural mesothelioma

Sivasundaram Karnan, Akinobu Ota, Muhammad Nazmul Hasan…·Yoshitaka Hosokawa

This study identifies FASN inhibition as a therapeutic strategy for NF2/CDKN2A-deficient MPM, showing reduced tumor growth in xenograft models.

3 citations

humanbulk RNA-seq

Cell BiologyNaturePeer-reviewedFeb 26, 2025

Extensive mutual influences of SMC complexes shape 3D genome folding

Han Zhao, Lirong Shu, Shiyi Qin…·Haoyue Zhang

This study investigates how SMC complexes interact during mitosis to shape 3D genome structure by engineering cohesin/condensin configurations on mitotic chromosomes.

33 citationstop 1%

humanChIP-seq

GenomicsbioRxivPreprintNov 9, 2023

Genome folding principles revealed in condensin-depleted mitotic chromosomes

Han Zhao, Yinzhi Lin, En Lin…·Haoyue Zhang

This study investigates genome folding in condensin-depleted mitotic chromosomes, revealing compartmentalization mechanisms distinct from interphase.

2 citations

experimental assay