Tânia F. Paulo

This study investigates disease tolerance in Drosophila by exposing it to heat-killed Pseudomonas entomophila, finding that mortality and fecundity reduction depend on exposure duration, sex, and bacterial virulence, with microbiota exacerbating effects.

The paper uses DEST 2.0 to analyze genetic variation in D. melanogaster across continents and time, identifying adaptation patterns and stable spatial genetic structures.

The paper identifies Peri-15a, a chitin-binding protein upregulated by immune activation in enteroendocrine cells, as essential for Vibrio cholerae colonization of arthropod intestines.

The paper develops a bioinformatics pipeline to integrate Drosophila melanogaster genomic data from diverse sources, creating a large dataset called DEST for population genetics analysis.