Paula I. Watnick

This study shows that acetylation of CRP K52 activates AR3, leading to changes in gene expression that affect sugar utilization and virulence in V. cholerae.

This paper identifies GulpR, a Drosophila GPCR expressed in enteroendocrine cells, and shows it regulates Tachykinin transcription, essential for lipid mobilization during nutrient limitation but not infection.

The paper identifies Peri-15a, a chitin-binding protein upregulated by immune activation in enteroendocrine cells, as essential for Vibrio cholerae colonization of arthropod intestines.

This study shows that Vibrio cholerae uses tryptophan to activate serotonin signaling in arthropod enteroendocrine cells, leading to IMD pathway activation and enhanced colonization.

This study shows that nitrite from V. cholerae nitrate respiration inhibits biofilm formation, but co-culturing with P. aminovorans reduces nitrite and enhances V. cholerae colonization.