Author

Zongjia Chen

The University of MelbourneORCID 0000-0002-8829-7042Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:structural biology· 2 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:metagenomics· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Spencer John WilliamsiD· 3 shared Alan CartmelliD· 2 shared Charles W.E. TomlinsoniD· 2 shared Conor J. CrawfordiD· 2 shared Edwin Alexander YatesiD· 2 shared Stefano ElliiD· 2 shared Abigail J. LaytoniD· 1 shared Adam DowleiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

Spencer John WilliamsORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 28, 2026

Structural basis for covalent inhibition of sulfatases by sulfamate warheads

Charles W.E. Tomlinson, Stefano Elli, Morgan E Batiste-Simms…·Alan Cartmell

This paper investigates why aryl sulfatases are inhibited by sulfamate warheads while carbohydrate sulfatases are not, using structural and computational analyses.

DOI 10.64898/2026.08.28.747710

bacteria (other)structural biology

𝕏 PostBluesky

BiochemistrybioRxivPreprintAug 18, 2026

Functional Differentiation of GH172 Arabinofuranosidases Through Divergent Quaternary Structures

Jennifer Ross, Moescha Hoopman, Florian Küllmer…·Elisabeth C. Lowe

The paper identifies functional and structural differences among three GH172 arabinofuranosidases from Dysgonomonas gadei using synthetic substrates, covalent inhibitors, and structural analysis.

DOI 10.64898/2026.08.13.744632

bacteria (other)structural biology

𝕏 PostBluesky

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedJul 10, 2025

Arylsulfamates inhibit colonic Bacteroidota growth through a sulfatase-independent mechanism

Conor J. Crawford, Charles W.E. Tomlinson, Christian Gunawan…·Alan Cartmell

The paper shows arylsulfamates inhibit Bacteroides growth on sulfated glycans via a lipid kinase, not carbohydrate sulfatases, and identifies resistance mechanisms.

7 citations

humanmetagenomics

𝕏 PostBluesky