PhysiologybioRxivPreprint
Beyond Glycogen Storage: AMPKγ2 Regulates Cardiac Hypertrophy and Electrophysiology via Myosin Interaction
Qianyun Ge, Kusumika Saha, Micah L. Burch…·Wandi Zhu
This study shows PRKAG2 variants cause cardiac hypertrophy and electrical changes in zebrafish, independent of glycogen storage, through AMPKγ2-myosin interactions.