Pieter J. Hoekstra

The paper conducts GWAS on brain volumes, identifies genetic loci, and develops polygenic scores with cross-ancestry predictive ability and causal links to neuropsychiatric disorders.

The paper identifies ten genes associated with ADHD-related grey matter brain networks in a sample of 899 individuals.

This study identifies two novel genetic loci associated with Tourette Syndrome through a genome-wide meta-analysis and integrates functional data to implicate specific genes.

The paper investigates gene-environment interactions related to tic severity by analyzing SNPs from GWASs of Tourette syndrome and related disorders in interaction with pre- and perinatal adversity.

This study analyzes structural brain asymmetries in ADHD using 39 datasets, finding small effects that do not meet study-wide significance thresholds.

This study identifies task-generic and task-specific connectivity modulations in ADHD brains across multiple tasks, finding reduced task-generic and increased task-specific connectivity in ADHD compared to controls and unaffected siblings.

This study identifies gene sets associated with Tourette Syndrome using genome-wide data, highlighting synaptic and immune-related pathways.

The paper investigates white matter microstructure in ADHD using tractography, finding no significant FA associations with diagnosis but links lower FA in the right cingulum angular bundle to hyperactivity/impulsivity symptoms.

The paper uses independent component analysis to identify reduced fronto-striatal volume in ADHD across two cohorts, showing consistent results across age and demographic differences.

The paper identifies structural brain network alterations in ADHD and their association with symptoms and cognitive function using source-based morphometry in a family cohort.

The paper examines structural brain differences in children and adolescents with aggressive behavior, finding subtype-specific volume reductions in regions linked to decision making and empathy.

This study compares structural brain differences across ADHD, ASD, and OCD using MRI data from multiple cohorts, finding disorder-specific alterations in brain volume and cortical thickness.

The paper examines functional connectivity differences in children and adolescents with disruptive behavior, finding distinct patterns for reactive and proactive aggression and callous-unemotional traits, emphasizing the role of comorbid symptoms.