Author

Lei Yu

Harvard UniversityORCID 0000-0002-8837-2022Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Lei Yu8 papers · The University of Texas Southwestern Medical Center

Biology Disciplines

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Cell Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Bingsen ZhangiD· 2 shared Edward T. ChouchaniiD· 2 shared Jiuchun ZhangiD· 2 shared Jonathan J. PetrocelliiD· 2 shared Nils BurgeriD· 2 shared Sanghee ShiniD· 2 shared Shelley M WeiiD· 2 shared Anita Reddy· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

Bingsen ZhangORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 24, 2026

Redox activation of ATG5 licenses autophagy upon nutrient restriction

Sanghee Shin, Ekaterina D. Korobkina, Claudia Lennicke…·Edward T. Chouchani

The paper identifies redox regulation of ATG5's Cys19 as critical for autophagy initiation under nutrient restriction in human cells and mice.

DOI 10.64898/2026.09.23.753803

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Cell BiologybioRxivPreprintSep 17, 2026

✦ In-depth digest

A quantitative redox proteome of the human muscle response to exercise

Lei Yu, Jonathan J. Petrocelli, Anita Reddy…·Edward T. Chouchani

Site-resolved redox proteomics of human muscle after three exercise types shows modality-specific cysteine oxidation, and a p62 Cys113 switch tied to autophagy in myotubes and mitochondrial remodeling in mice.

DOI 10.64898/2026.09.15.751463

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BioinformaticsbioRxivPreprintMar 31, 2021

Emerging SARS-CoV-2 mutation hotspots associated with clinical outcomes

Xianwu Pang, Pu Li, Lifeng Zhang…·Yanling Hu

The paper identifies SARS-CoV-2 mutation hotspots linked to severe clinical outcomes using genomic and RNA-seq data from 209,551 sequences and 321 samples.

1 citation

whole-genome sequencingbulk RNA-seq

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