Author

Shelley M Wei

Dana-Farber Cancer InstituteORCID 0009-0002-8359-1880Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Organism:mouse· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:database / resource· 1

Frequent Co-Authors

Bingsen ZhangiD· 3 shared Edward T. ChouchaniiD· 3 shared Nils BurgeriD· 3 shared Sanghee ShiniD· 3 shared Haopeng XiaoiD· 2 shared Jiuchun ZhangiD· 2 shared Jonathan J. PetrocelliiD· 2 shared Lei YuiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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3 shared papersCell Biology

Bingsen ZhangORCID

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3 papers

Recent·Most cited

Redox activation of ATG5 licenses autophagy upon nutrient restriction

Sanghee Shin, Ekaterina D. Korobkina, Claudia Lennicke, Nils Burger, Bingsen Zhang, Haopeng Xiao, Yaoyu Wang, Jonathan J. Petrocelli, Shelley M Wei, David Wood, Lei Yu, Xiaomei Zhang, María C. Pérez-Matos, Muneeb A Sharif, Jiuchun Zhang, , Edward T. Chouchani

The paper identifies redox regulation of ATG5's Cys19 as critical for autophagy initiation under nutrient restriction in human cells and mice.

bioRxiv · Sep 24, 2026 · PreprintCell Biology

A quantitative redox proteome of the human muscle response to exercise

Lei Yu, Jonathan J. Petrocelli, Anita Reddy, Carlos Henríquez‐Olguín, Nils Burger, Sanghee Shin, Bingsen Zhang, Taylor Covington, Markus Waldeck‐Weiermair, Jiuchun Zhang, Shelley M Wei, Thomas E. Jensen, Christian T. Voldstedlund, Christian Strini Carl, Bente Kiens, , Edward T. Chouchani

Site-resolved redox proteomics of human muscle after three exercise types shows modality-specific cysteine oxidation, and a p62 Cys113 switch tied to autophagy in myotubes and mitochondrial remodeling in mice.

bioRxiv · Sep 17, 2026 · PreprintCell Biology✦ In-depth digest

A druggable redox switch on SHP1 controls macrophage inflammation

Mei Ying Ng, Meredith Nicole Nix, Guangyan Du, Ivan Davidek, Nils Burger, Sanghee Shin, Sean T. Toenjes, Haruna Takeda, Megan Cheah Xin Yan, Bingsen Zhang, Haopeng Xiao, Shelley M Wei, Hyuk‐Soo Seo, Sirano Dhe‐Paganon, Thomas E. Wales, , Edward T. Chouchani

This paper identifies a druggable redox switch on SHP1 that controls macrophage inflammation by developing a covalent agonist targeting a specific cysteine residue.

Nature Chemical Biology · Mar 12, 2026Peer-reviewedBiochemistry