Cell BiologybioRxivPreprint
Regulatory T cells modulate bone marrow stromal cell osteogenesis by activating ROCK-myosin axis and cell contractility
Eylem Baysal, Azzurra Margiotta, Shuntaro Yamada…·Salwa Suliman
DOI 10.64898/2026.01.16.699899
Author
Haukeland University HospitalORCID 0000-0002-8842-534XUnclaimed ORCID profile · follow to get notified of new preprints
2 papers
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Eylem Baysal, Azzurra Margiotta, Shuntaro Yamada…·Salwa Suliman
Kristina Xiao Liang, Atefeh Kianian, Anbin Chen…·Laurence Albert Bindoff
This study shows that POLG mutations in astrocytes cause mitochondrial dysfunction and neurotoxicity, leading to neuronal death through altered metabolism and reactive astrocyte behavior.