Author

Atefeh Kianian

University of Bergen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

Anbin CheniD· 1 shared Cecilie Katrin KristianseniD· 1 shared Charalampos TzoulisiD· 1 shared Gareth J. SullivaniD· 1 shared Jessica FurrioliD· 1 shared Kristina Xiao LiangiD· 1 shared Laurence Albert BindoffiD· 1 shared Lena Elise HøylandiD· 1 shared

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2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Anbin ChenORCID

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1 paper

Recent·Most cited

Stem cell derived astrocytes with POLG mutations and mitochondrial dysfunction including abnormal NAD+ metabolism is toxic for neurons

Kristina Xiao Liang, Atefeh Kianian, Anbin Chen, Cecilie Katrin Kristiansen, Yu Hong, Jessica Furriol, Lena Elise Høyland, Mathias Ziegler, Torbjørn Kråkenes, Charalampos Tzoulis, Gareth J. Sullivan, Laurence Albert Bindoff

This study shows that POLG mutations in astrocytes cause mitochondrial dysfunction and neurotoxicity, leading to neuronal death through altered metabolism and reactive astrocyte behavior.

bioRxiv · Dec 20, 2020 · PreprintNeuroscience