Cell BiologybioRxivPreprint
FXR-mediated recruitment of PPP1CB suppresses SMAD2/3 phosphorylation to mitigate pulmonary fibrosis
Wenqi Li, Qiong Wu, Yongzhi Lu…·Jinsai Shang
This study identifies FXR as a suppressor of pulmonary fibrosis by interacting with PPP1CB to reduce SMAD2/3 phosphorylation, showing therapeutic potential with TERN101.
DOI 10.64898/2026.07.24.740478