Mapping enhancer-gene regulatory interactions from single-cell data
Maya U. Sheth, Wei‐Lin Qiu, X. Rosa Ma, Andreas R. Gschwind, Evelyn Jagoda, Anthony S. Tan, James Galante, Judhajeet Ray, Dulguun Amgalan, Hjörleifur Einarsson, Bram L. Gorissen, Danilo Dubocanin, Christopher S. McGinnis, Jacob Huang, Glen Munson, , Robin Andersson
The paper introduces scE2G models to predict enhancer-gene regulatory interactions from single-cell data and demonstrates their performance across multiple cell types and perturbations.
Nature Genetics · Aug 1, 2026Peer-reviewedGenetics