NeurosciencebioRxivPreprint
Neuronal PARIS-STAT3 axis drives tau pathology and glial activation in Alzheimers disease
Ji-Yang Song, Fatih Akkentli, Heejin Jo…·Ted M. Dawson
This study shows that PARIS in neurons activates STAT3, leading to tau pathology and glial activation in Alzheimer's disease, and identifies the PARIS-STAT3 pathway as a therapeutic target.
DOI 10.64898/2025.12.06.692741