Cancer BiologybioRxivPreprint
AMPK- and cGAS-Mediated Dual Sensing of Glucose and dsDNA Synergizes to Enhance Antitumor Immunity
Ruyuan Zhou, Jingyan Pei, Shasha Chen…·Pinglong Xu
This study identifies a mechanism where AMPK and cGAS-STING signaling synergize through glucose and dsDNA sensing to enhance antitumor immunity in melanoma and colorectal cancer.
DOI 10.1101/2025.02.15.638470