Pinglong Xu

This study identifies oxidative mtDNA B-Z transitions activating ZBP1 as a key mechanism in APAP-induced liver failure and shows TH107854 can reverse this process.

This study reveals that oncogenic EGFR mutations exploit the STING-TBK1 immune pathway to enhance DNA damage repair and therapeutic resistance in NSCLC.

This study identifies a mechanism where AMPK and cGAS-STING signaling synergize through glucose and dsDNA sensing to enhance antitumor immunity in melanoma and colorectal cancer.