NeurosciencebioRxivPreprint
cGAS-mediated IFN-I signaling contributes to disease progression in drug-refractory epilepsy
Yige Huang, Li Fan, Man Ying Wong…·Li Gan
This study identifies cGAS-mediated IFN-I signaling as a driver of disease progression in drug-refractory epilepsy, showing that targeting cGAS reduces epileptic phenotypes and inflammation.