Author

Qianying He

University of Arizona

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Andrew Tang· 2 shared Patrick T. RonaldsoniD· 2 shared Rui R. ChangiD· 2 shared Abhijit DasguptaiD· 1 shared Angel C Leslie· 1 shared Barbora Vagnerova· 1 shared Boer Xie· 1 shared Branden Lau· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Andrew Tang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

HLA-DRB1*15:01 drives sex- and age-dependent microglial activation and neuroimmune signaling

Elsa M. Reyes‐Reyes, Dhanalakshmi Chinnasamy, Fabian‐Xosé Fernandez, Michael Trial, Vincent Nguyen, Qianying He, Carolina Figueroa, Angel C Leslie, David Robert Bradford, Jean‐Paul L. Wiegand, Kathleen E. Rodgers

This study shows that HLA-DRB1*15:01 causes age- and sex-dependent microglial activation and neuroimmune signaling changes linked to cognitive impairment and inflammation in the CNS.

bioRxiv · Mar 14, 2026 · PreprintNeuroscience

Human-mouse proteomics reveals the shared pathways in Alzheimer's disease and delayed protein turnover in the amyloidome

Jay M. Yarbro, Xian Han, Abhijit Dasgupta, Ka Yang, Danting Liu, Him K. Shrestha, Masihuz Zaman, Zhen Wang, Kaiwen Yu, Dong Geun Lee, David Vanderwall, Mingming Niu, Huan Sun, Boer Xie, Ping‐Chung Chen, , Junmin Peng

Alzheimer's mouse model proteomes capture 30% (amyloid-only models) to 42% (adding tau and splicing models) of consensus human AD protein changes; in 5xFAD, plaques slow degradation of plaque-associated proteins.

Nature Communications · Feb 11, 2025Peer-reviewedBiochemistry✦ In-depth digest

Novel Master Regulators of Microglial Phagocytosis and Repurposed FDA-approved Drug for Treatment of Alzheimer Disease

Kuixi Zhu, Qianying He, Sheng‐Feng Tsai, Dinusha C. Maheepala, Marc Henrion, Syed Shujaat Ali Zaidi, Branden Lau, Andrew Tang, Mika P. Cadiz, Rachel Hodos-Nkhereanye, Sara Moein, Melissa L. Alamprese, David Alan Bennett, Philip L. De Jager, John D. Frye, , Rui R. Chang

The paper identifies key driver genes for microglial phagocytosis and repurposes riluzole to treat Alzheimer's Disease by enhancing SLC1A2 activity.

bioRxiv · Oct 19, 2022 · PreprintNeuroscience