Author

Dalin Rifat

Johns Hopkins UniversityORCID 0000-0002-8918-5173Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Eric L. NuermbergeriD· 3 shared Barry N. KreiswirthiD· 1 shared Ghader Bashiri· 1 shared J. I. Lee· 1 shared James Sacchettini· 1 shared Jean-Philippe Lanoix· 1 shared Jin Lee· 1 shared Liang CheniD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

Eric L. NuermbergerORCID

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3 papers

Recent·Most cited

Rv2061c, a Putative F420-Dependent Oxidoreductase, is Required for Tolerance to Malachite Green and Other Antimicrobials and Oxidative Stress Protection in Mycobacterium tuberculosis

Dalin Rifat, Thomas R. Ioerger, Eric L. Nuermberger

This study identifies Rv2061c as a critical F420-dependent oxidoreductase that protects Mycobacterium tuberculosis from antimicrobials and oxidative stress.

bioRxiv · Oct 16, 2026 · PreprintMicrobiology

In vitro and in vivo validation of cwlM and pbpB essentiality for viability and resistance to imipenem in Mycobacterium abscessus

J. I. Lee, Si‐Yang Li, Dalin Rifat, Natalia E. Kurepina, Liang Chen, Barry N. Kreiswirth, Eric L. Nuermberger

This study validates cwlM and pbpB as essential genes for Mycobacterium abscessus viability and imipenem resistance using CRISPRi in vitro and in vivo.

bioRxiv · Mar 8, 2024 · PreprintMicrobiology

Mutations in Rv2983 as a novel determinant of resistance to nitroimidazole drugs in Mycobacterium tuberculosis

Dalin Rifat, Si-Yang Li, Thomas Ioerger, Jean-Philippe Lanoix, Jin Lee, Ghader Bashiri, James Sacchettini, Eric Nuermberger

This paper identifies Rv2983 as a novel gene conferring resistance to nitroimidazole drugs in Mycobacterium tuberculosis and highlights the challenges in detecting such resistance.

bioRxiv · Oct 31, 2018 · PreprintMicrobiology