NeurosciencebioRxivPreprint
The paradoxical effects of K+ channel gain-of-function are mediated by GABAergic neuron hypoexcitability and hyperconnectivity.
Amy N. Shore, Sophie Colombo, William F. Tobin…·Matthew C. Weston
The paper investigates how a gain-of-function K+ channel variant causes seizures by reducing inhibitory neuron excitability and increasing network hyperconnectivity.
2 citations