Author

Christopher D. Bostick

Columbia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Assay:electronic health records· 3 Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:software / tool· 1

Frequent Co-Authors

David B. GoldsteiniD· 3 shared Michael J. BolandiD· 3 shared Wayne N. FrankeliD· 3 shared Cathleen M. LutziD· 2 shared Michael A. BeaumontiD· 2 shared Mu YangiD· 2 shared Sabrina Petri· 2 shared Amy N. ShoreiD· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersNeuroscience

David B. GoldsteinORCID

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3 papers

Recent·Most cited

The paradoxical effects of K+ channel gain-of-function are mediated by GABAergic neuron hypoexcitability and hyperconnectivity.

Amy N. Shore, Sophie Colombo, William F. Tobin, Sabrina Petri, Erin R. Cullen, Soledad Domínguez, Christopher D. Bostick, Michael A. Beaumont, Damian J. Williams, Dion Khodagholy, Mu Yang, Cathleen M. Lutz, Yueqing Peng, Jennifer N. Gelinas, David B. Goldstein, , Matthew C. Weston

The paper investigates how a gain-of-function K+ channel variant causes seizures by reducing inhibitory neuron excitability and increasing network hyperconnectivity.

bioRxiv · Mar 5, 2020 · PreprintNeuroscience

Modeling and treating GRIN2A developmental and epileptic encephalopathy in mice

Ariadna Amador, Christopher D. Bostick, Heather E. Olson, Jurrian Peters, Chad R. Camp, Daniel K. Krizay, Wenjuan Chen, Wei Han, Weiting Tang, Ayla Kanber, Sukhan Kim, Jia Jie Teoh, Sabrina Petri, Hunki Paek, Ana Kim, , Wayne N. Frankel

This study models GRIN2A-related DEE in mice, identifies seizure and behavioral abnormalities, and evaluates treatment strategies.

bioRxiv · Aug 16, 2019 · PreprintNeuroscience

meaRtools: an R Package for the Analysis of Neuronal Networks Recorded on Microelectrode Arrays

Sahar Gelfman, Quanli Wang, Yifan Lu, Diana Hall, Christopher D. Bostick, Ryan S. Dhindsa, Matthew Halvorsen, Keisha Melodi McSweeney, Ellese Cotterill, Tom Edinburgh, Michael A. Beaumont, Wayne N. Frankel, Slavé Petrovski, Andrew S. Allen, Michael J. Boland, , Stephen J. Eglen

The paper introduces meaRtools, an R package for analyzing neuronal network data from microelectrode arrays, demonstrating its ability to identify epilepsy-like phenotypes in Celf4 knockout mice.

PLoS Computational Biology · Oct 1, 2018Peer-reviewedNeuroscience