Author

Hannah R. Megathlin

Jackson LaboratoryORCID 0000-0002-8934-7654Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Basile TarchiniiD· 1 shared Ellen I. HartigiD· 1 shared Kristian Lorenzo· 1 shared Valerie Erhardt· 1 shared Vishnu HosuriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperGenetics

Basile TarchiniORCID

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1 paper

Recent·Most cited

Large-Scale Genome-Wide Optimization and Prediction of the Cre Recombinase System for Precise Genome Manipulation in Mice

Valerie Erhardt, Ellen I. Hartig, Kristian Lorenzo, Hannah R. Megathlin, Basile Tarchini, Vishnu Hosur

This study optimizes the Cre-Lox system for efficient genome modification in mice by analyzing factors like loxP distance, Cre-driver strain, and breeding age.

Genome biology · Apr 4, 2025Peer-reviewedGenetics