Basile Tarchini

This study optimizes the Cre-Lox system for efficient genome modification in mice by analyzing factors like loxP distance, Cre-driver strain, and breeding age.

The paper presents a large annotated dataset of cochlear hair cells for machine learning applications in hearing research.

This study investigates the role of GPR156 in mouse and zebrafish sensory organs, showing it relays orientation and transduction information but not afferent selectivity for direction-specific stimuli.

This study identifies Nrxn3 as essential for ribbon-synapse assembly in hair cells across mouse and zebrafish models, showing its critical role in synaptic function without affecting acoustic startle behavior.

This study identifies the distinct roles of GNAI proteins in mouse auditory hair cell polarization and morphogenesis, revealing compensatory mechanisms and novel defects upon their inactivation.

The paper identifies STK32A as a kinase regulated by EMX2 that determines hair cell planar polarity orientation in the mouse inner ear, with STK32A promoting bundle alignment opposite to EMX2's effect.

This study identifies MPDZ's role in maintaining apical cytoskeleton patterning in hair cells, showing its necessity for stereocilia alignment and preventing hearing loss in Mpdz mutants.