Author

Pin‐Xian Xu

Icahn School of Medicine at Mount SinaiORCID 0000-0002-8957-6780Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Aarthi RamakrishnaniD· 1 shared Bernd FritzschiD· 1 shared Christopher M. ReidiD· 1 shared Corey C. HarwelliD· 1 shared Daniel J. Merk· 1 shared Eunyoung ParkiD· 1 shared Grace H. HwangiD· 1 shared Huihui JiangiD· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Aarthi RamakrishnanORCID

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2 papers

Recent·Most cited

The Eya1 phosphatase mediates Shh-driven symmetric cell division of cerebellar granule cell precursors

Daniel J. Merk, Pengcheng Zhou, Samuel M. Cohen, Maria F. Pazyra‐Murphy, Grace H. Hwang, Kristina J. Rehm, Jose Alfaro, Christopher M. Reid, Xuesong Zhao, Eunyoung Park, Pin‐Xian Xu, Jennifer Ai-wen Chan, Michael J. Eck, Kellie J. Nazemi, Corey C. Harwell, Rosalind A. Segal

This study identifies the Shh-Eya1 regulatory axis as critical for promoting symmetric cell divisions in cerebellar granule cell precursors by coordinating spindle orientation and cell fate determinants.

Developmental Neuroscience · Jan 1, 2020Peer-reviewedNeuroscience

Brg1 controls neurosensory cell fate commitment and differentiation in the mammalian inner ear

Jin Xu, Jun Li, Yong‐Hwee Eddie Loh, Ting Zhang, Huihui Jiang, Bernd Fritzsch, Aarthi Ramakrishnan, Li Shen, Pin‐Xian Xu

This study identifies Brg1's role in specifying neurosensory lineage and differentiation in the mammalian inner ear by interacting with Eya1/Six1 and regulating chromatin structure.

bioRxiv · Oct 3, 2018 · PreprintDevelopmental Biology