Author

Yuewei Zhan

Hong Kong University of Science and TechnologyORCID 0000-0002-8959-3978Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:diffusion model· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Martín Echavarría GalindoiD· 2 shared Shuchen WangiD· 2 shared Yong LaiiD· 2 shared Chengyuan LiniD· 1 shared George McDonald ChurchiD· 1 shared Hor Yue Tan· 1 shared Liang CuiiD· 1 shared Lingpeng KongiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersSynthetic Biology

Martín Echavarría GalindoORCID

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2 papers

Recent·Most cited

DAPE-PD: Diffusion adaptation of genomic foundation model enables tailored-generation of cis-regulatory DNA

Martín Echavarría Galindo, Shansan Gong, Yuewei Zhan, Shuchen Wang, Lingpeng Kong, Yong Lai

DAPE-PD adapts a genomic foundation model into a diffusion model to generate functional cis-regulatory DNA sequences across three non-model gut commensals.

bioRxiv · Oct 27, 2026 · PreprintSynthetic Biology

Sourdough starter-inspired living materials grown from probiotic consortia with engineered division-of-labor

Shuchen Wang, Yiqi Xu, Yuewei Zhan, Martín Echavarría Galindo, Sherman Cheuk Yui Chau, Liang Cui, William M. Shaw, Wen Jun Xie, Hor Yue Tan, Chengyuan Lin, Xue Jiang, Zhaoxiang Bian, Peter C. Dedon, George McDonald Church, Timothy K. Lu, , Yong Lai

The paper describes the creation of SINERGY, a synthetic sourdough starter using engineered microbial consortia with division-of-labor modules for biosensing and drug delivery.

bioRxiv · Oct 9, 2025 · PreprintSynthetic Biology