Author

Jie Kang

Tsinghua UniversityORCID 0000-0002-8991-2844Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Xiaobo Wang· 2 shared Yan Shi· 2 shared Alexey SergushicheviD· 1 shared Alwin J. van der HamiD· 1 shared Arnoud H. de RuiD· 1 shared Bart EvertsiD· 1 shared Béatrice M. F. WinkeliD· 1 shared Cao HuangiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Xiaobo Wang

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Hierarchical Immune Suppressive Functions of Regulatory T Cells Built on Mechanical Force

Xinyi Liu, Cao Huang, Xiaobo Wang, Jie Kang, Chunlin Zou, Yanni Xu, Longyan Wu, Yan Shi

This study identifies a hierarchical mechanical force-based model of Treg suppression, showing that stable adhesion is required for localized cytokine delivery to dendritic cells.

bioRxiv · May 21, 2026 · PreprintImmunology

O-GlcNAcylation and low glycolysis underpin Th2 polarization by dendritic cells

Leonard R. Pelgrom, Marjolein Quik, José Javier Fernández, Thiago A. Patente, Graham A. Heieis, Alexey Sergushichev, Jie Kang, Xiaobo Wang, Justine Dontaine, Marie-Sophie Fabre, Frank Otto, Alwin J. van der Ham, Lisa W. Bloemberg, Marion H. König, Béatrice M. F. Winkel, , Bart Everts

This study identifies O-GlcNAcylation and reduced glycolysis as key factors in Th2 polarization by dendritic cells, showing their role in immune synapse regulation and TCR signaling.

bioRxiv · Feb 5, 2026 · PreprintImmunology