Author

José Javier Fernández

Leiden UniversityORCID 0000-0001-7552-0076Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexey SergushicheviD· 1 shared Alwin J. van der HamiD· 1 shared Arnoud H. de RuiD· 1 shared Bart EvertsiD· 1 shared Béatrice M. F. WinkeliD· 1 shared Cornelis Hendrik HokkeiD· 1 shared Frank OttoiD· 1 shared Graham A. HeieisiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alexey SergushichevORCID

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1 paper

Recent·Most cited

O-GlcNAcylation and low glycolysis underpin Th2 polarization by dendritic cells

Leonard R. Pelgrom, Marjolein Quik, José Javier Fernández, Thiago A. Patente, Graham A. Heieis, Alexey Sergushichev, Jie Kang, Xiaobo Wang, Justine Dontaine, Marie-Sophie Fabre, Frank Otto, Alwin J. van der Ham, Lisa W. Bloemberg, Marion H. König, Béatrice M. F. Winkel, , Bart Everts

This study identifies O-GlcNAcylation and reduced glycolysis as key factors in Th2 polarization by dendritic cells, showing their role in immune synapse regulation and TCR signaling.

bioRxiv · Feb 5, 2026 · PreprintImmunology