Sean B. Wilson

This paper develops PT-enhanced kidney organoids with S3-like cells to model physiological responses in CKD, showing improved functionality and scalability.

This study classifies off-target and indeterminate cell types in human kidney organoid differentiation using single-cell transcriptomics.

This study shows that hPSC-derived distal nephron epithelium can adopt ureteric or nephric duct-like identities in vitro in response to extracellular signals.

This study generates integrated kidney assembloids by co-culturing nephron-forming and nephric duct progenitors, demonstrating functional connectivity between nephrons and a single collecting duct.

DevKidCC classifies kidney organoid cell subtypes accurately by comparing datasets to a reference model trained on human fetal kidney single-cell RNA-seq data.